There was a talk on C-SPAN recently by a history professor about the Lost Colony (Roanoke Island). When a ship came along and offered the original set of colonists a chance to go back to England, everyone took advantage of the offer...except for three men who were off exploring or hunting at the time and were left behind. Their fate is unknown—no sign that they were found by the second set of colonists so may have died before they arrived.
Recently they have found evidence that the colony moved out to the Hatteras Island for some unknown reason, maybe raids by Indians, maybe some other reason. Then the colony was wiped out by a hurricane that washed away all traces of the colony...................