Google AI:
Nicotinamide (also known as niacinamide) is a form of vitamin B3 used to treat and prevent niacin deficiency, address various skin conditions, and reduce the risk of certain skin cancers. It is also being studied for potential therapeutic uses related to aging and other health issues.
For skin conditions
Nicotinamide is widely used in both oral and topical forms to improve skin health.
Acne: Its anti-inflammatory properties can help to reduce acne lesions and regulate oil production.
Rosacea and atopic dermatitis: Nicotinamide can help reduce inflammation and soothe irritation caused by these conditions.
Hyperpigmentation: It can help treat melasma and other skin discoloration by brightening the complexion.
Aging skin: Topical nicotinamide may improve skin elasticity and reduce the appearance of fine lines and wrinkles.
Skin barrier function: It helps rebuild the skin’s lipid barrier, which improves hydration and protects against irritants.
For skin cancer prevention
Studies have shown that oral nicotinamide can help prevent new non-melanoma skin cancers (basal cell and squamous cell carcinomas) and actinic keratoses in high-risk patients. It does this by boosting cellular energy and enhancing DNA repair, which protects against UV damage.
For niacin deficiency
Nicotinamide is a primary treatment for pellagra, a disease caused by severe niacin deficiency. In contrast to niacin (nicotinic acid), nicotinamide does not cause the unpleasant flushing that can be associated with higher doses.
For other medical research
Scientists are also investigating nicotinamide’s potential role in treating other conditions:
Type 1 diabetes: Nicotinamide may help delay the onset of type 1 diabetes, but more research is needed.
Cancer therapy: It is being studied as an agent that can make cancer cells more susceptible to radiation therapy and chemotherapy.
Neurological diseases: As a precursor to the coenzyme NAD+, it is being explored for its potential to help prevent neurodegenerative diseases.
Important considerations
While nicotinamide is generally well-tolerated, it is a water-soluble vitamin and is not a substitute for a balanced diet. Supplements should only be taken under medical supervision, especially at high doses.
Well cool! I take 1000mg of this daily. After reading the book “Niacin, The Real Story” by Abram Hoffer and others. Don’t recall anything about skin cancer but it’s good to know!