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[Myrddin]

When COVID was a hot topic, Dr Sabine Hazan discovered that the COVID infection wiped out the Bifidobacteria in the gut. She compared healthy and unhealthy individuals and did a fingerprint of the biome in each category. Missing Bifidobacteria was a key marker for the unhealthy group. Below is a summary generated by grok in html form for this post.

Key Findings from Sabine Hazan's Gut Microbiome Research

• COVID-19 Severity (2022): Severe COVID-19 patients showed low microbiome diversity, depleted Bifidobacterium and Faecalibacterium, and higher Bacteroides, while healthy/mild cases had high diversity and protective bacteria, inversely correlating with symptom severity. (Signal Transduction and Targeted Therapy, 2022)
• ASD and GI Symptoms (2020): A triplet with ASD and GI issues had lower diversity, higher Bacteroidetes/Firmicutes ratio (0.67 vs. 0.17–0.24), reduced Bifidobacterium (0.79% vs. 9–16%), and increased Proteobacteria/Blautia compared to healthy siblings, suggesting dysbiosis links to ASD. (Journal of Personalized Medicine, 2020)
• Vitamin C and Bifidobacteria (2022): Vitamin C supplementation increased Bifidobacterium levels, enhancing healthy microbiomes and infection resistance, while low baseline levels marked unhealthy, infection-prone states. (Future Microbiology, 2022)
• COVID-19 Discordant Family (2022): Infected family members had lower Bifidobacterium and diversity compared to healthy, uninfected members, indicating pre-existing dysbiosis predicts susceptibility. (Frontiers in Medicine, 2022)
• Ivermectin and Immunity (2022): Ivermectin may feed Bifidobacterium, reducing inflammation in COVID-19; unhealthy profiles with low Bifidobacterium showed worse outcomes. (Journal of Inflammation Research, 2022)
• Anxiety and Microbiome (2024): Anxious patients exhibited dysbiosis with altered bacterial patterns compared to non-anxious controls, linking healthy microbiomes to better mental health. (Journal of Personalized Medicine, 2024)
• Mother-Infant Microbiome (2024): High maternal Bifidobacterium protected newborns from severe outcomes, while low levels increased vulnerability, highlighting early-life microbiome importance. (Nutrients, 2024)