[woweeitsme]

Of course, after taking this pill for an extended time period, you will begin to grow a third arm and have uncontrollable vomiting.

[z3n]

Sylvester Stallone - - - - - - - - - - Aldo Sterone

[PGalt]

Thanks for posting.

[Snowybear]

Sounds like a statin, which I absolutely refuse to take but I don’t need it anyway.

I highly recommend staying away from statins.

-SB

[ChildOfThe60s]

I had one doctor who wanted to put me on blood pressure medicine after one reading in his office. I refused. Other than that they seem to accept my statement that it stays in normal ranges at home.

[RideForever]

What if your ‘hypertension’ is actually caused by a protein spike causing inflammation from within blood vessels, and the swelling from within the vessels is causing the ‘high blood pressure’?

[Big Red Clay]

Bkmk

[Getready]

The drug inhibits the normal body synthesis of aldosterone. One of the effects of aldosterone is to increase sodium and water in blood leading to higher blood pressures.
There are three drugs already on the market for years ..but they inhibit the effect of aldosterone by blocking the aldosterone at the cellular site(receptor).
New drug decrease synthesis of aldosterone. Similar side effects but different chemicals. But both effect aldosterone activity.
.Recommend finding original study publication and reading it to get a better understanding of the relevance of the drug to modern antihypertensive regimens.
IMHO

[catnipman]

baxdrostat is still “investigational”, not having yet been approved by the FDA for human consumption, but if/when baxdrostat IS approved, it’ll cost only, say, $1,000/dose if it really is much more effective than existing medications ...

[daniel1212]

Blood pressure is strongly influenced by a hormone called aldosterone, which helps the kidneys regulate salt and water balance. Some people produce too much aldosterone, causing the body to hold onto salt and water. This aldosterone dysregulation pushes blood pressure up and makes it very difficult to control. Addressing aldosterone dysregulation has been a key effort in research over many decades, but it has been so far difficult to achieve. Baxdrostat works by blocking aldosterone production, directly addressing this driver of high blood pressure (hypertension).

Promising for some.

[algore]

Doctors love to put you on any kind of recurring medicines cause that causes them to have a recurring revenue stream.

[SuperLuminal]

Dang!
For the past 15 years, my blood pressure (measured & charted at least 4 days a week at cardiologist’s request) has been between 129 and 139... My wife’s BP ranges from 105-118...

We are both on Metoprolol: Wife=25mg... Me=50mg...

When my wife and I go to his office, we both always measure BP in the 145-155 range... Even our BP machines, which we take with us to verify the home-charted readings, agree with those high office readings...

[LadyDoc]

Most bp meds lower bp by 10mm

And spironolactone is an aldosterone blocker.