I found few for your cancer, but the following one showed a new therapy approach that showed this success (overall survival (OS)):
Different outcomes for positive, negative pancreatic cancer patients receiving chemoradiation and systemic therapy
“The primary endpoint for the trial was OS, which was only improved for patients with node-negative disease (5-year OS 48.1% for patients on the Chemo+CRT arm versus 28.6% on the Chemo arm).”
https://medicalxpress.com/news/2024-06-outcomes-positive-negative-pancreatic-cancer.html
It sounded like you may be considered node negative right now. If so, consider this option, which greatly increases overall survival at five years.
As this condition is rare and has less on it, my final review becomes the most manual review, which is a search of the studies off search terms from the NIH PubMed site:
Why do I limit my use of AI? Because the output is beset by political correctness around what are the most professionally-agreed upon answers, which hides the one-off studies of something novel. Why do I like “novel?” Because it can be harmless to try out, yet, not have a Cochrane Review-level of “authority.” I have had great success with these “hidden”opportunities. “Novel” does not mean “scientifically implausible,” however.
General website searches can also bring up these actionable study references, but often, study outcomes are just included in a paragraph with no named study to go back and reference. I do find search engines have the same bias (“weighting”) that can prevent less known research from sparking an idea path to then follow with a deeper dive. The NIH site seems largely free from bias, compared with most search engines.
Ampullary cancer is less the 0.5% of pancreatic type cancers. Pancreatic cancer is termed "peri-Ampullary". The number of studied cases is small, yet the survival statistics aren't very encouraging.
Thank you for your research and links.