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Has anyone explored DAO deficiency in connection to larger systemic or even oncologic issues?

I’m working with my oncologist at Duke University Hospital to learn more about this. I gave him a few journal articles and peaked his interest.

I made my own DAO by sprouting green peas in the dark for 10 days. I did 5 lbs of them and then Greece dried the sprouts.

I powdered the results and put them in vegetarian size 0 capsules. The result is far stronger in DAO content than the DAO supplements available. It’s just pea sprouts so I think you could eat a cereal bowl of the powder and it would not hurt you. I made a gallon of the pea sprouts powder in my first batch, enough to fill about 10,000 capsules.

The results are very profound and immediate. Much to my surprise, the results are experienced 10 minutes after taking a capsule.

I’m now working on having them lab tested for DAO level. They are 100% green peas sprouts, nothing else.

I just give them away. They are so easy and cheap to make that I enjoy helping people get better.

I’m turning a stainless steel bread proofing cabinet into a sprouting cabinet with automatic spray rinsing and fans for air circulation. That will provide a constant supply of sprouts.

I have an extra large commercial freeze dryer so I can do about 8 to 10 lbs of peas every two days.

I’m just having fun.

Has anyone explored DAO deficiency in connection to larger systemic or even oncologic issues?

Yes -- me and ChatGPT.

As I’ve mentioned before, my lymphoma (mantle cell lymphoma) was driven by a chromosomal translocation—t(11;14)—a well-documented genetic trigger for this form of cancer.

Recently, I had an in-depth discussion with an AI assistant about a potential link between DAO deficiency and cancer risk, particularly how a lack of DAO activity can lead to chronic histamine overload, inflammation, and immune system stress.

The theory I’m exploring is this: DAO deficiency → histamine/tyramine buildup → systemic inflammation and cellular stress → increased risk of DNA damage or mutation → possible contribution to cancer development, especially in genetically susceptible individuals.

Of course, this is speculative—but the idea that chronic inflammatory conditions may prime the environment for oncogenic mutations is gaining traction in research circles.

I'd love to hear from anyone else who’s explored the histamine-cancer or nutrigenomic-oncology connection, or who has experience with DAO-related issues and chronic illness like yourself.

Here's the link to the conversation if you’re curious:

https://tggtest.com/tggmisc/freerepublic/dao_lymphoma.htm