I have usually just saved seeds which produced well and used them as seedlings. (I save seeds with the pulp in a cup, and cover + let them sit for 2 or 3 days, then rise with warm warm water in a strainer, and spread out on a paper bag to dry well, and thus have a good germination rate, thank God.)
Often I loose track, and thus some hybrids are unknowingly planted, but I read that plants that grow from seed saved from hybrid plants generally are less vigorous, more variable, and usually have smaller blossoms and yield less than their parents. These the seeds won’t “breed true.”
More detail: https://ipm.missouri.edu/MPG/2014/8/Why-Not-Save-Hybrid-Seeds/
And here is a source I was reading on https://www.gardeningchannel.com/tomato-diseases-how-to-fight-septoria-leaf-spot/ (seek diagnosis of what I see every year)