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The amino acid glycine appears to be 2/3 of this tripeptide. The write up speaks to body issues with glycine, which we can normally make, when we are younger. I have posted threads on GlyNAC, which is half glycine, and it helps a number of health issues. Both glycine and cysteine are not created well by our bodies and we seem to not utilize what we get from complete proteins, either, when older.

This compound, or glycine by itself, may be helpful at preventing artery plaques.

1 posted on 04/27/2025 8:04:53 PM PDT by ConservativeMind
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2 posted on 04/27/2025 8:05:29 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

I was thinking about taking 10 grams/day of glycine anyway for glynac and general longevity reasons (plus it helps improve the skin); now I definitely will be doing so.


4 posted on 04/27/2025 10:07:36 PM PDT by Ancesthntr ("The right to buy weapons is the right to be free." The Weapons Shops of Isher)
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To: ConservativeMind

TRI methyl glycine is available now as a supplement. You can purchase pharmaceutical grade on Amazon. It’s been used for years as a liver detoxifier.

https://www.amazon.com/s?k=tri-methyl+glycine&crid=3GZ2XJNQE8FVX&sprefix=%2Caps%2C112&ref=nb_sb_ss_recent_2_0_recent

How is this different from what this study was using?


5 posted on 04/28/2025 2:36:49 AM PDT by nikos1121
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To: ConservativeMind

Article a bit misleading. It prevents or blocks further atherosclerosis. It does not reverse the process.

I like the fact that it reduces inflammation.

It makes sense that if it does this is in the liver maybe it does it elsewhere.

I recently had a CRP test that showed some elevation, indicating inflammation. Which is the cause of heart disease, not cholesterol etc. Sugar is the biggest culprit.

Would ge interesting to go on the trimethyl glycine in a supplement dosage of at least 650mg or more per day, and redo the CRP after 90 days.

Your body pretty much detoxifies within 90 days, esp the GI lining providing that you stop any pollutants, including alcohol.

Interesting article. Thanks.


7 posted on 04/28/2025 2:42:57 AM PDT by nikos1121
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To: ConservativeMind

I take both glycine/NAC because they have both individual roles which I dimly understand and because together they create —in just the right amounts—glutathion which is a big antioxident. I also take TMG—originally because I was takin NMN or B3 or niacinimide...and its said that these supplements deplete TMG. But I have cycled off all of them for now. And I still take TMG. Now for no reason except habit. It would be nice if TMG did reduce or prevent arterial plaques. But its not clear that TMG is an analog for the peptide mentioned in this article.


11 posted on 04/28/2025 8:36:34 AM PDT by ckilmer
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To: ConservativeMind
I always thought fatty liver disease came from being overweight.

Turns out, not always.

That does not seem fair.

14 posted on 04/28/2025 9:02:24 AM PDT by Harmless Teddy Bear ( Not my circus. Not my monkeys. But I can pick out the clowns at 100 yards.)
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