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To: maddog55

“ Numerous scientific studies have proven there is no link between cholesterol levels and heart attacks and strokes.”

Not true. High cholesterol, particularly high LDL levels are well-linked with cholesterol plaques in the arteries, and there are some specific genetic relationships , known as familial hypercholesterolemias, between high cholesterol and cardiovascular diseases.

The drug in this article goes after a specific cause of such disease, lipoprotein (a). If you have this variant, this drug sounds very promising.


32 posted on 04/06/2025 8:56:53 AM PDT by VanShuyten ("...that all the donkeys were dead. I know nothing as to the fate of the less valuable anima)
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To: VanShuyten

True and here’s just a few...

https://www.bhf.org.uk/informationsupport/heart-matters-magazine/news/behind-the-headlines/cholesterol-and-statins

The researchers, led by Dr Uffe Ravnskov at the University of Lund, Sweden, looked at 19 existing studies which considered the association between ‘bad’ LDL cholesterol levels and the overall risk of death in people aged over 60. They concluded that 92 percent of people with a high cholesterol level lived longer, and called for a re-evaluation of the guidelines for cardiovascular prevention, “in particular because the benefits from statin treatment have been exaggerated.”

Abstract: https://pubmed.ncbi.nlm.nih.gov/30198808/

For half a century, a high level of total cholesterol (TC) or low-density lipoprotein cholesterol (LDL-C) has been considered to be the major cause of atherosclerosis and cardiovascular disease (CVD), and statin treatment has been widely promoted for cardiovascular prevention. However, there is an increasing understanding that the mechanisms are more complicated and that statin treatment, in particular when used as primary prevention, is of doubtful benefit.

https://medicalxpress.com/news/2018-10-ldl-cholesterol-heart-disease.html

“There have been decades of research designed to deceive the public and physicians into believing that LDL causes heart disease, when in fact, it doesn’t,” said David Diamond, Ph.D., a professor in USF’s Departments of Psychology and Molecular Pharmacology & Physiology, and a co-author of the article. “The research that has targeted LDL is terribly flawed. Not only is there a lack of evidence of causal link between LDL and heart disease, the statistical approach statin advocates have used to demonstrate benefits has been deceptive.”


35 posted on 04/06/2025 11:29:07 AM PDT by maddog55 (The only thing systemic in America is the left's hatred of it!)
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To: VanShuyten
High cholesterol, particularly high LDL levels are well-linked with cholesterol plaques in the arteries,

#1 Correlation is not the same as causation.
#2 The LDLs lowered by most (if not all) by statins are the wrong LDLs that cause problems. You do know there are many different LDLs, didn't you?
#3 Instead of statins, with their many known side effects, an improvement of diet and exercise would be the best course of improvement on health.
#4 Cholesterol all alone is a very poor bio-marker of health which is something the health industry overlooks because of the enormous money generated by statins.

36 posted on 04/06/2025 2:48:51 PM PDT by BipolarBob (I'm trying to be good but sometimes it's too much fun being bad.)
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