I live very near the site - locals have long believed there is very little mystery. The colonists eventually intermarried with the local Indian tribes, most likely the Lumbee who do have blond hair, blue eyed descendants. They had to do what they had to do to survive.
Interestingly, Trump signed an EO that should lead to the Lumbee being formally recognized as a tribe
That very well could be.
Assume they went to Hatteras Island, then get hit by a hurricane, many perished and a remnant were rescued by the Lumbee and moved away.................
From your description of the Lumbee, it sounds like they did a bit of doing all righty.
My nephew married a Lumbee. At the wedding, I met the family. They were indeed an assortment of appearances, but mostly African-American. One difference would be that their noses are not the soft contour of an African nose.
Fayette, North Carolina iirc was their home region.