“Results”
“Treatment induced significant (p <0.05) reductions in body weight, fat mass, and liver injury, while VO2peak (p <0.05) and non-esterified fatty acid suppression (p = 0.06) were improved. Both groups exhibited reductions in total energy intake, hemoglobin A1c, hepatic insulin resistance, and liver fat (p <0.05). Compared to control, treatment induced a two-fold increase in peripheral insulin sensitivity which was significantly related to higher VO2peak and resolution of liver disease.”
“For the first time, these results show that an improvement in peripheral (but not hepatic) insulin sensitivity and systemic markers of muscle function (i.e. cardiorespiratory fitness) were strongly related to resolution of liver disease. Extrahepatic disposal of substrates and improved fitness levels supported histologic improvement, confirming the addition of exercise as crucial to lifestyle interventions in MASH.”
You can reverse more than a few health issues in life, naturally.
My advice to older Freepers is to avoid loosing weight too fast. 7 years ago I lost 40 pounds in 6 months and that thickened up my bile, gave me gallstones, and ended up in the removal of my gallbladder a year later.
“...one group followed a restricted diet and a high intensity interval training exercise program for 10 months....
This is such a shock. A good diet and exercise can reduce fat and improve diebetes. Losing excess fat around organs is a good start to health. But you’ll notice they are not claiming over extended weight losses of over 10 pounds at a time. They are claiming of a consant weight loss of under 3 pounds monthly which is a safe weight loss for extended success of a person at 200 pounds. It’s relevent. But it is also the same thought process the American Diebetic Association, the AMA, and other medical associations and teaching institutes recommend. So, what’s the big deal? I’m missing their point.
wy69
I had a liver test done earlier this year. During the preceeding 9 months, I had lost about 30 pounds and changed my exercise program to include HIIT.
I had the test because the outside of my liver was mottled, as one would expect from someone with liver issues cirhossis of the liver. I drank for 20 years and stopped when I was age 40. that was more than 30 years ago.
The testing guy said my liver was clear. He said it looked much better than most. I think that had to do with the weight loss and the HITT.