You can only use blood of the same type; with the exception of O- blood which is universal and rare. So unless you share the same blood type the answer is now. I am sure you COULD make it happen but that’s not how it typically works. They take from the blood bank.
The blood is usually filtered in various ways, whether it can be or is filtered to remove spike protein I can’t answer. Maybe.
I am sorry for your wife’s troubles. I had a severe ulcer attack my hemoglobin dropped below 7. I couldn’t stand up. Blood pressure dropped incredibly low. I needed two blood transfusions, a whole heck of a lot of saline including 1 liter open wide just to bring the volume back up, 3 days in the hospital for “observation” even after most symptoms went away and my hemoglobin level rose. The only good thing out of all that was they ran every test imaginable on me. Scanned every organ and tested every one of my precious bodily fluids (well, except for one). So other than the ulcer, which is now healed, everything is good for me. My advice is don’t let them just write it up as “Ulceritis colitis”. If she’s going to be in the hospital check all the vital organs just in case. You’re there you might as well check everything you can. Most of it is via ultrasound. Make sure her kidneys, bladder, heart and lungs are normal. They can do most of that right in the hospital bed.
You can only use blood of the same type; with the exception of O- blood which is universal and rare.
https://www.redcrossblood.org/donate-blood/blood-types.html