“Flammability: R32 has a lower flammability compared to R22 and R410A, making it a safer option for air conditioning systems.”
“Pressure: R32 operates at a lower pressure compared to R22 and R410A, which can result in smaller and lighter components for air conditioning systems.”
“Compatibility: R32 is compatible with existing air conditioning systems that use R22 and R410A, making it a suitable alternative for retrofitting existing systems. However, it’s important to consider compatibility with the specific system and components before retrofitting to R32.”
https://www.climamarket.eu/blog/en/r32-refrigerant-everything-you-need-to-know/
I’m just quoting. I have no previous knowledge about the truth of those quotes.
Note that the website is in the EU. I don’t know if R32 is legal for central air use in the USA. I have and use a R32 window unit.
I believe this R32 or equiv was in the fridge in that British high-rise apartment fire that killed 70 a few years back.
The stories try to hide that.