Posted on 05/29/2024 7:00:00 PM PDT by ConservativeMind
Antihypertensive drugs are associated with an increased risk for eczematous dermatitis in older adults, and the effect sizes are largest for diuretics and calcium channel blockers, according to a study.
Morgan Ye, M.P.H. and colleagues examined whether antihypertensive drug use is associated with eczematous dermatitis in a longitudinal cohort study of individuals aged 60 years and older without eczematous dermatitis at baseline.
The researchers found that the overall prevalence of eczematous dermatitis was 6.7% among 1,561,358 older adults during a median follow-up of six years. The incidence of eczematous dermatitis was higher among those receiving versus those not receiving antihypertensive drugs (12 versus 9 of 1,000 person-years of follow-up).
Participants who received any antihypertensive drugs had a significantly increased risk for any eczematous dermatitis in adjusted analyses (hazard ratio, 1.29). When assessing each antihypertensive drug class individually, the largest effect sizes were seen for diuretics and calcium channel blockers, while the effect sizes were smallest for angiotensin-converting enzyme inhibitors and β-blockers (hazard ratios, 1.21, 1.16, 1.02, and 1.04, respectively).
"Although additional research is needed to understand the mechanisms underlying the association of antihypertensive drug use and eczematous dermatitis, these data could be helpful to clinicians to guide clinical management when an older patient presents with eczematous dermatitis," the authors write.
(Excerpt) Read more at medicalxpress.com ...
But I am old enough to remember the good old days before we had these medicines, when young people died of strokes from severe high blood pressure.
WTH is eczematous dermatitis and what does it lo like?
They don’t put enough information in these stories.
Now I have to look up eczematous dermatitis!
Ok, now I wish I hadn’t searched images!
I have RA, take a beta blocker and I’m old.
What does the three Ps mean? Being positive here.
Currently using hydrocortisone topically to stop the itch. Yes, I take lisinopril.
Actually, ACE-I drugs effectively had no risk of this. The increased likelihood was likely within the margin of error.
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