Scientific American had an article about research findings from over twenty years ago that proved stress makes the blood brain barrier permeable.
Another researcher that was the protege of the Australian that discovered bacteria causes stomach ulcers found bacteria in Alzheimer’s plaques.
Before you go head to head with the genetic windmill read the book, “Not In Our Genes”.
If I were you I would focus on the gut biome with emphasis on Akkermansia muciniphila and the correlations between the lack thereof and medical issues.
IOW, you may learn more relevant information from having your stool tested for the bacterial content than a genetic test.
The P glycoprotein gene is the gatekeeper for the blood brain barrier
If you have a problem with that gene then you may have additional problems.
If you have a problem with genes that clear toxins in the brain you may be more at risk.
I have both those genetic problems.
I have had a brain MRI and waiting for the doctor visit to tell me how much of a mess it is with white matter, etc. I have read the report. Now I need the expert.
What good does that report do. Really not much. They cant do much other than tell you to work on risk factors for stroke etc. tell me to take statins which I dont want to do. I have to figure out another way.
Also I had no idea that reflux can increase risk of stroke.