Clinical Annotation for rs1799971 (OPRM1); tianeptine; Depressive Disorder, Major and suicidal ideation (level 3 Toxicity)
https://www.pharmgkb.org/clinicalAnnotation/1450935171
LOL....sheesh...yep...another drug that my genes have a problem with. Anyone that has to take risky drugs should have a full genome test just so you know what to look out for like this:
“AA Patients with the AA genotype may be at an increased risk of developing treatment emergent suicidal ideation (TESI) when treated with tianeptine as compared to patients with the AG or GG genotypes. Other genetic and clinical factors may also affect suicidal ideation in patients.”