I have a desk. And I am prepared to get under it. I’ll be fine.
Unless your underground shelter (where your desk is located) is air-tight, the blast from the nuclear explosion will suck out the oxygen, even though the shelter is strong enough (and far enough away from ground zero) to survive the blast.
Also, unless you have sufficient compressed air tanks and CO2 scrubbers in the shelter, your air ventilation system will need to have HEPA and charcoal filters designed to trap fallout particulates and volatile fission decay products (e.g., I-131).
Portable power (and sufficient fuel) for A/C will also be needed. If your shelter has a water supply from an underground well, that is a plus.
Living at and having a fallout shelter located somewhere just east of the Rockies (but not near Cheyenne Mountain Complex) may also minimize the chances of an enemy nuclear weapon landing nearby.
