Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

How vitamin D3 helps allergic asthma
Medical Xpress / Friedrich–Alexander Univ / Journal of Allergy and Clinical Immunology: Global ^ | April 24, 2023 | Janina C. Grund et al

Posted on 04/25/2023 8:07:12 AM PDT by ConservativeMind

A vitamin D3 deficiency can lead to severe symptoms, for example in people suffering from allergic asthma. This has already been shown in several studies. However, we still do not fully understand how exactly this vitamin influences the cellular inflammatory reaction in the body.

A team of researchers has now demonstrated for the first time how taking vitamin D3 can alter the cellular inflammatory reaction in allergic asthma and alleviate asthma symptoms.

Doctoral candidate Janina Grund and the members of the working group have investigated the clinical manifestation of asthma in pre-school children and adults in the context of vitamin B3 levels in their blood and taking vitamin D3 supplements.

The team of researchers discovered that children and adults who took vitamin D3 supplements had less pronounced asthma symptoms and presented with less severe asthma, at the same time as requiring fewer steroids for inhalation. In certain cells in the blood of people with higher levels of vitamin D3, the scientists discovered greater quantities of the protein blimp-1, that is responsible for controlling the immune response of T helper cells.

In order to gain a better understanding of the mechanism, Janina Grund investigated the effects administering vitamin D3 has on the immune response in mice. Once again, the vitamin led to less severe cases of asthma.

She also found fewer allergy-inducing antibodies (IgE) that are responsible for certain allergic diseases such as hay fever, asthma or eczema. Administering higher doses of vitamin D3 even triggered an anti-inflammatory reaction in the immune system, specifically with the messenger substance IL-10 and cells that create blimp-1.

Interestingly, the working group was able for the first time to prove that the vitamin has an effect on long-lived memory T cells that are key to the long-term immune response in the case of asthma.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS:
From the study, it looks like asthmatic kids clustered around 11 ng/mL of blood Vitamin D level, on a graph.

That’s pretty deficient. If you know of a child with asthma, please get their Vitamin D level checked.

1 posted on 04/25/2023 8:07:12 AM PDT by ConservativeMind
[ Post Reply | Private Reply | View Replies]

To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 04/25/2023 8:07:53 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Anyone who lives north of the 36th parallel should be taking 5000mg of vitamin D3 daily.


3 posted on 04/25/2023 8:20:50 AM PDT by Signalman
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

If you are supplementing with D3 make sure you are also taking the Mk7 form of vitamin K2. It helps with the proper absorption of the D3 from what I remember.


4 posted on 04/25/2023 8:27:03 AM PDT by copaliscrossing (The truth is always your friend.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: copaliscrossing

My doctor told me for some reason or another to avoid K2.


5 posted on 04/25/2023 8:54:10 AM PDT by MachIV
[ Post Reply | Private Reply | To 4 | View Replies]

To: ConservativeMind

So since I have been on D3 for the last 3 years I can now have a cat back in my house? 🐈‍⬛


6 posted on 04/25/2023 8:55:30 AM PDT by MachIV
[ Post Reply | Private Reply | To 1 | View Replies]

To: MachIV
My doctor told me for some reason or another to avoid K2.

Hmmm.... Interesting. I wonder if it is the MK7 form? I know that can make a difference but your comment is the first I have heard of a negative take on K2/MK7 supplementation to D3.
7 posted on 04/25/2023 9:00:41 AM PDT by copaliscrossing (The truth is always your friend.)
[ Post Reply | Private Reply | To 5 | View Replies]

To: MachIV

My sister was told the same when she was on Coumadin


8 posted on 04/25/2023 9:04:47 AM PDT by LilFarmer
[ Post Reply | Private Reply | To 5 | View Replies]

To: ConservativeMind

I have adult onset allergy asthma and I credit D3 and all the other supplements I take daily for my ability to function. I took a breathing test at the pulmonary doctor’s office in November and when I went back into his office to consult about it he was telling me I shouldn’t be able to walk across the room without collapsing.

He said “Are you even able to grocery shop?”. I’m like laughing as I tell him I’m going to the grocery after I leave his office. Then he asks if I’m able to run the vacuum cleaner. So I pull up a picture of the driveway at our rural property which is fairly steep and tell him I walk up and down it all the time. I get a little out of breath but no worse than just being somewhat out of shape. He just shakes his head. The Zelenko protocol which we take everyday is really fantastic.


9 posted on 04/25/2023 10:50:14 AM PDT by Georgia Girl 2 (The only purpose of a pistol is to fight your way back to the rifle you should never have dropped)
[ Post Reply | Private Reply | To 1 | View Replies]

To: copaliscrossing
Copied from the internet:

In foods MK4 is found in dairy and meats but at levels much smaller than those studied and shown to be helpful in human clinical trials. While there are different forms of vitamin K2, only MK4 has been shown in clinical trials to maintain strong bones, promote healthy bone density and bone matrix.

I also take notes, and have MK4 & MK7 noted (as to take with Vit D3).
Just an FYI

10 posted on 04/25/2023 2:35:41 PM PDT by spankalib
[ Post Reply | Private Reply | To 7 | View Replies]

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson