[Bull Snipe]

“first of all, there was lots of manufacturing in Southern states”

That was not really the case. According to the 1860 Census

Manufacturing Investment, North $892 million, South $113 million

Manufacturing operations, North 110,000, South 18,000

Manufacturing workers, North 1.3 million, South 110,000; this included slaves working in Southern manufacturing operations.

[BroJoeK]

BJK: "“first of all, there was lots of manufacturing in Southern states”

Bull Snipe: That was not really the case. According to the 1860 Census"

You are right depending on perspective.
That's because in 1860 across the entire globe there were only three or four highly industrialized regions:

1. The Northern United States
2. England's central industrial region
3. Northern France and Belgium
4. To a lesser degree, northern to eastern Germany

So sure, in comparison to these relatively small regions, "the South" was less industrialized.
However, it was more industrialized than pretty much any other region, and that's why I say "there was lots of manufacturing in Southern states."

And the key point is that politically, there were lots of Southerners who supported protective tariffs to Make America Great by Putting Americans First.
I've mentioned Presidents George Washington & James Madison (Virginia), Andrew Jackson (Tennessee) and Senator Henry Clay (Kentucky), and we could add to those, in his younger years even South Carolina Senator Calhoun.
Later Calhoun switched sides, but my point remains that not all Southerners opposed protective tariffs, tariffs that also protected their own agricultural products and manufacturing.

In the 1828 vote on the "Tariff of Abominations" while 29 Northern representatives voted against, 17 Southern representatives voted for.
So, tariffs were not all about "North vs. South".