https://market-ticker.org/akcs-www?post=247200&page=1
It's apparently possible to custom build a virus which escapes immunity in jabbed people due to changes in the spike protein, but whose pathogenicity is due to changes elsewhere in the virus.
We generated chimeric recombinant SARS-CoV-2 encoding the S gene of Omicron in the backbone of an ancestral SARS-CoV-2 isolate and compared this virus with the naturally circulating Omicron variant. The Omicron S-bearing virus robustly escapes vaccine-induced humoral immunity, mainly due to mutations in the receptor binding motif (RBM), yet unlike naturally occurring Omicron, efficiently replicates in cell lines and primary-like distal lung cells. In K18-hACE2 mice, while Omicron causes mild, non-fatal infection, the Omicron S-carrying virus inflicts severe disease with a mortality rate of 80%. This indicates that while the vaccine escape of Omicron is defined by mutations in S, major determinants of viral pathogenicity reside outside of S.
In a new study from WalletHub, cities were ranked on how much inflation is rising. The study pointed to the year-over-year inflation rate of 8.2% last month, but noted that some cities are feeling costs increase more than others. In the report, 23 Metropolitan Statistical Areas were examined. The site looked at the Consumer Price Index information available for the most recent month and compared it to two months ago and one year prior.
Inflation is going up the most in the Phoenix-Mesa-Scottsdale area of Arizona, with Atlanta-Sandy Springs-Roswell, Georgia, Miami-Fort Lauderdale-West Palm Beach, Florida, Tampa-St. Petersburg-Clearwater, Florida, Baltimore-Columbia-Towson, Maryland, and Dallas-Fort Worth-Arlington, Texas, coming in after.
In California, San Diego-Carlsbad ranked number eight, with Los Angeles-Long Beach-Anaheim at number 12, Riverside-San Bernardino-Ontario at number 13, and San Francisco-Oakland-Hayward ranking at number 22.
The areas where inflation is going up the most in California all voted for President Joe Biden in the 2020 presidential election
https://www.dailywire.com/news/california-cities-getting-hit-hardest-by-inflation-and-how-they-voted