Most of our modern meds are created from herbs and other natural sources with this and that added in to make it a pharmaceutical or prescription. That’s why the FDA and others hate herbal medicine and natural unregulated supplements so much. No money in it if people can just grow it, pick it, or dig it up. Even Ivermectin started from a compound discovered in the soil in Japan.
My grandmother was part Cherokee and only used natural native herbs. I don’t think she ever took a pharmaceutical.