I’ve done it. Whacked a porcupine while restraining a very upset dog on a leash.
One handed shotgun.
I regularly shoot flying clays one handed and over the years have shot a few game birds one handed.
I don’t recommend doing so with magnum loads they do sting a bit.
Practice is what it takes.
Over 55 years of using both I find semi’s a bit more picky about ammo and a bit less reliable.
On the inexpensive end of the scale I would go with a pump.