Aspirin Use Is Associated With Decreased Mechanical Ventilation, Intensive Care Unit Admission, and In-Hospital Mortality in Hospitalized Patients With Coronavirus Disease 2019

journals.lww.com ^ | Oct 21, 2020 | Jonathan H. Chow, Ashish K. Khanna, Shravan Kethireddy, et al

[ransomnote]

[H/T chuck allen]

Authors: Chow, Jonathan H. MD^*; Khanna, Ashish K. MD, FCCP, FCCM^†,‡; Kethireddy, Shravan MD^§; Yamane, David MD^∥; Levine, Andrea MD^¶; Jackson, Amanda M. MD^#; McCurdy, Michael T. MD^¶; Tabatabai, Ali MD^¶,**; Kumar, Gagan MD^§; Park, Paul MD^††; Benjenk, Ivy RN, MPH^*; Menaker, Jay MD; Ahmed, Nayab MD^§§; Glidewell, Evan MD^∥∥; Presutto, Elizabeth MD^††; Cain, Shannon MD^¶¶; Haridasa, Naeha BS^*; Field, Wesley MD^§§; Fowler, Jacob G. BS^∥∥; Trinh, Duy MD^††; Johnson, Kathleen N. BS^∥∥; Kaur, Aman DO^§§; Lee, Amanda BS^††; Sebastian, Kyle MD^∥∥; Ulrich, Allison MD^††; Peña, Salvador MD, PhD^∥∥; Carpenter, Ross MD^††; Sudhakar, Shruti MD^††; Uppal, Pushpinder MD^††; Fedeles, Benjamin T. MD, Capt, USAF, MC^††; Sachs, Aaron MD^††; Dahbour, Layth MD^††; Teeter, William MD^**,##; Tanaka, Kenichi MD^‡‡‡; Galvagno, Samuel M. DO, PhD^**; Herr, Daniel L. MD^**; Scalea, Thomas M. MD^**,‡‡; Mazzeffi, Michael A. MD, MPH^***Author Information

Anesthesia & Analgesia: April 2021 - Volume 132 - Issue 4 - p 930-941

doi: 10.1213/ANE.0000000000005292

 

EXCERPTS ONLY. DETAILS OF STUDY AT LINK. 

Excerpt: "In summary, our analysis suggests that aspirin use may have beneficial effects in patients with COVID-19. Mechanistically, these findings are plausible given aspirin’s irreversible antiplatelet effect and the frequent hypercoagulability observed in COVID-19 patients. The results of our study are intriguing, especially because aspirin has been thoroughly studied in chronic cardiovascular disease, has a well-described safety profile, and is readily available throughout the world. The preliminary, hypothesis-generating nature of our study provides the basis for a larger study, which will be needed to confirm our findings and assess the extent to which the relationships observed in our study are causal. Until a randomized controlled trial of aspirin is performed, it is imperative to exercise cautious optimism and deliberately balance aspirin’s known risks against its potential benefits in patients afflicted by COVID-19."

 

Aspirin Use Is Associated With Decreased Mechanical Ventilat... : Anesthesia & Analgesia (lww.com)

 

[DesertRhino]

And it’s an anti-inflamatory also. Interesting.

[Fido969]

Take two asprins and call me in the morning.

[AFreeBird]

Aspirin has been my drug of choice over all the others (Tylenol, Aleve, etc), pretty much my whole life.

[HollyB]

Perhaps because it’s a blood thinner and helps against the clotting.

Aspirin has been discussed for over a year now for those reasons.

[crusty old prospector]

Seems like it was used during the Spanish Flu. But overuse led to deaths.

[SkyDancer]

When the FDA/CDC find OTC meds that help fight COVID they’ll find a way to ban them.

[WLusvardi]

Is C-19 really Respiratory Syncytial (clotting) Virus which has been around since 1884 in the US? Has identical symptoms. Tests can’t distinguish the difference.

[lee martell]

Thanks for that boiled down summary.
Apparently, I read the headline and thought they were saying the exact opposite.

[HollyB]

My dad used to take one every day. His dr told him it was not good for his gut and to stop. He had a stroke very shortly after that (within a couple of weeks). His dr was a fool by not for seeing how the abrupt change would effect his blood.

[ransomnote]

Thanks for that boiled down summary.
Apparently, I read the headline and thought they were saying the exact opposite.
~~~~~~~~~~~~~~~~

I had the same experience until I found their summary. It’s likely a universal reaction to the way it’s written.

[Colt1851Navy]

Colchicine is better than aspirin, discovered in Ancient Egypt, actual retail value-$1.00 a hundred.

[Irenic]

dittos...I seldom to ever take Tylenol.

[BobL]

Don’t horses take aspirin after surgery?

[Revel]

Well then we must ban it!

[HollyB]

Interesting. It certainly appears it is behaving similarly.
After having AML and struggling with platelet levels after remission for years, it is one of my main concerns about getting the vax. I do my best to try and stay healthy against the virus. I don’t have full control tho. But, I have full control over getting the shot. Both the virus and vax seem to mess with platelets. I do a lot of praying. But, I will not live in fear.

[gov_bean_ counter]

Which leads me to my undereducated belief that a person can be otherwise healthy and have a strong inflammatory response to virus infection.

Perhaps that is what is happening to people getting sick from the shot???

[MachIV]

My doc put me on a 1-a-day regimen of aspirin 12 years ago. Probably still alive today partially thanks to that. Of course if I accidentally cut myself I bleed like a stuck hog for a while.

[glorgau]

> When the FDA/CDC find OTC meds that help fight COVID they’ll find a way to ban them.

Yep, can’t let some superstitious use of 10¢ tree bark keep people from needing $3000 anti virals.

[SkyDancer]

Well okay if you have gout or lots of uric acid in your system.