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There are some common sources of manganese one could temporarily restrict, but it is a mineral used in a few key processes, so restriction would be a trade off.

Of course, if this specific bacteria had become life threatening, one may want to experiment with restriction.

1 posted on 08/10/2021 7:48:50 AM PDT by ConservativeMind
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To: ConservativeMind

2 posted on 08/10/2021 7:52:19 AM PDT by Red Badger (Homeless veterans camp in the streets while illegal aliens are put up in hotels.....................)
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To: ConservativeMind

Also helpful to stop eating sugar and bread. Feeds EVERY disease there is.


3 posted on 08/10/2021 8:01:35 AM PDT by montag813
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To: ConservativeMind

Interesting. Thanks for posting.

Pneumo is quite common and many carry it in their noses or throats without disease. I am guessing I do.
I may want to get that pneumovax now that I think about it.
A really easy diplo to recognize under the microscope, docs I have worked with will treat from a gram stain.


4 posted on 08/10/2021 9:29:12 AM PDT by MarMema
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To: ConservativeMind
Thread title needs to be re-worded from : "Starving pneumonia-causing bacteria of its favorite 'food' holds promise for new antibiotics (manganese) "

"Starving pneumonia-causing bacteria of its( favorite 'food' -manganese,) ....holds promise for new antibiotics "

5 posted on 12/10/2023 7:53:13 AM PST by urtax$@work
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To: ConservativeMind

https://ods.od.nih.gov/factsheets/Manganese-HealthProfessional/

Manganese is an essential trace element that is naturally present in many foods and available as a dietary supplement. Manganese is a cofactor for many enzymes, including manganese superoxide dismutase, arginase, and pyruvate carboxylase [1,2]. Through the action of these enzymes, manganese is involved in amino acid, cholesterol, glucose, and carbohydrate metabolism; reactive oxygen species scavenging; bone formation; reproduction; and immune response [3-7]. Manganese also plays a role in blood clotting and hemostasis in conjunction with vitamin K [5].

Manganese is absorbed in the small intestine through an active transport system and, possibly, through diffusion when intakes are high [2]. After absorption, some manganese remains free, but most is bound to transferrin, albumin, and plasma alpha-2-macroglobulin. Manganese is taken up by the liver and other tissues, but the mechanism of this process is not well understood [1,2].

The human body contains about 10 to 20 mg manganese, of which 25% to 40% is in bone [1,2]. The liver, pancreas, kidney, and brain also contain manganese. The body maintains stable tissue manganese concentrations through regulatory control of manganese absorption and excretion [5]. More than 90% of absorbed manganese is excreted via bile into the feces, and a small amount is reabsorbed [1,2,4,5]. Very little is excreted in urine.

Manganese status is difficult to assess and not routinely measured in clinical practice. Normal whole blood concentrations of manganese range from 4 to 15 mcg/L [1], but they are highly variable and their utility as a status indicator is unclear [4]. Some studies that measured serum or plasma manganese concentrations in apparently healthy adults have shown mean serum concentrations of 1.04 mcg/L and mean plasma concentrations of 1.28 mcg/L [4,8]. Large variations in manganese intakes appear to affect these concentrations somewhat [9]. However, these concentrations often do not correlate well with typical manganese intakes, so whether they are useful indicators of manganese status is not clear [4].

Although urinary manganese concentrations decrease with severe deficiency, it is not clear whether they are useful indicators of manganese status when intakes are within the normal range [4].


Maybe STOP the supplements but beyond that?


6 posted on 12/10/2023 7:59:13 AM PST by PeterPrinciple (Thinking Caps are no longer being issued but there must be a warehouse full of them somewhere.)
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