Posted on 09/06/2020 9:12:12 PM PDT by ConservativeMind
Nicotinamide riboside (NR) is pretty amazing. It has already been shown in several studies to be effective in boosting metabolism....
As mice, like all mammals, age, the regenerative capacity of certain organs (such as the liver and kidneys) and muscles (including the heart) diminishes. Their ability to repair them following an injury is also affected. This leads to many of the disorders typical of aging.
Under normal conditions, these stem cells, reacting to signals sent by the body, regenerate damaged organs by producing new specific cells. At least in young bodies.
This is why the researchers wanted to "revitalize" stem cells in the muscles of elderly mice. And they did so by precisely targeting the molecules that help the mitochondria to function properly. "We gave nicotinamide riboside to 2-year-old mice, which is an advanced age for them," said the researcher. "This substance, which is close to vitamin B3, is a precursor of NAD+, a molecule that plays a key role in mitochondrial activity. And our results are extremely promising: muscular regeneration is much better in mice that received NR, and they lived longer than the mice that didn't get it."
A breakthrough for regenerative medicine
Parallel studies have revealed a comparable effect on stem cells of the brain and skin. "This work could have very important implications in the field of regenerative medicine," said Auwerx. "We are not talking about introducing foreign substances into the body but rather restoring the body's ability to repair itself with a product that can be taken with food." This work on the aging process also has potential for treating diseases that can affect - and be fatal - in young people, like muscular dystrophy (myopathy).
So far, no negative side effects have been observed following the use of NR, even at high doses.
(Excerpt) Read more at medicalxpress.com ...
Ping of interest.
“...my wife and I take 300 mg a day of Niagen..”
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Same here. Sadly, it’s not making me younger... but I feel good. ;-)
too bad its expensive as fork.
What brand are you taking?
TIA
I don’t have an organ. Will it work on my 42-year old piano ?
TRU NIAGEN NAD+ Booster for Cellular Repair & Energy Metabolism (Nicotinamide Riboside) - 300mg Vegetarian Capsules, 300mg Per Serving - 30 Day Bottle (3 Pack)
Ping
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It offers many benefits for aging skin since it is also a skin-restoring ingredient. It has the ability to enhance the appearance of fine lines, uneven skin tone, enlarged pores, weakened skin surface, and dullness, among others.
Thank you!
We take Niagen.
Thanks!
In the 90 capsule form under an Amazon subscription, you can drive the cost down to under $1.20 a day, I believe. We get the 15% discount when we have five subscriptions fill in that month (so we everything all at once for awhile).
Looking at this article and others... this supplement is a little pricey and promises just about everything with few if any side effects:
Easily Converted Into NAD+
Activates Enzymes That May Promote Healthy Aging
May Help Protect Brain Cells
May Lower Heart Disease Risk
May aid weight loss
May lower cancer risk
May help treat jet lag
May promote healthy muscle aging
https://www.healthline.com/nutrition/nicotinamide-riboside#bottom-line
My problem with this is that I am skeptical of unproven supplements that promise so much and are a bit on the pricey side. There are so many other supplements that make the same types of claims. That is why the dietary supplement “industry” has grown to a $40 Billion dollar a year snake oil type enterprise. Everyone wants to believe that they can take a magic pill that will make them healthier and live longer. 99% of the time they do less than the health benefits from an inexpensive but reputable multivitamin.
No, give it to your cats—provided they have “organs.”
The 90 capsule single bottle should be cheaper per pill than multiple 30 counts.
Ping for nicotinamide riboside.
“Easily Converted Into NAD+
Activates Enzymes That May Promote Healthy Aging
May Help Protect Brain Cells
May Lower Heart Disease Risk
May aid weight loss
May lower cancer risk
May help treat jet lag
May promote healthy muscle aging”
A lot of “Mays” there.
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