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To: ETCM

I recall reading something - probably here - about T cells perhaps conferring some resistance to Covid-19 in people who had encountered previous Corona viruses. I can’t find that specific article, now; but this seems related:

http://directorsblog.nih.gov/2020/07/28/immune-t-cells-may-offer-lasting-protection-against-covid-19/


22 posted on 08/22/2020 4:43:27 PM PDT by Jamestown1630 ("A Republic, if you can keep it.")
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To: Jamestown1630
I recall reading something - probably here - about T cells perhaps conferring some resistance to Covid-19 in people who had encountered previous Corona viruses.

T-cell immunity seems to be important in respiratory virus infections in general, including SARS. This paper is from 2018:

The CD8 T Cell Response to Respiratory Virus Infections

This excerpt from the text speaks to the cross-protection of different strains:

...robust memory CD8 T cell responses efficiently reduced lung viral titers in the absence of neutralizing antibodies following RSV, IAV, or SARS secondary infections. An important property of CD8 T cells is that they often recognize conserved viral proteins, allowing for cross-protection between different virus strains.

So, it's possible that people who have been previously exposed to a similar coronavirus might have a much better immune response to COVID-19.

23 posted on 08/22/2020 7:11:33 PM PDT by ETCM
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