Vik Malhotra
Vik Malhotra
7 hours ago (edited)
I have actually been cautious on zinc because zinc metalloproteases might be involved in TMPRSS2 upregulation which may be involved in the infection pathway: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375694/ and https://www.pnas.org/content/117/13/7001 But it’s interesting that it helps with VWF clearance. So, wondering how to balance the two. Is the TMPRSS2 upregulation something to be concerned about with zinc?