so perhaps why Ace inhibitors MIGHT be a problem with covid 19 ..we have seen that theorized but havent really seen a definitive answer. the more I read the more I think this was an experiment for whatever reason that went wrong. why do malaria drugs if given early seem to work when malaria is from a parasite?
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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.116.309602
We propose the hypothesis that high levels of Ang II, which cause hypertension, protect against cerebral malaria.
Furthermore, it is important to consider that angiotensin receptor blockers, by shifting circulating Ang II to stimulate the AT2 receptor, may be protective against cerebral malaria, whereas ACE inhibitors would reduce the levels of Ang II, possibly increasing the likelihood of developing cerebral malaria on infection with Pfalciparum. In this context, it may be preferable to use angiotensin receptor blockers rather than ACE inhibitors for the treatment of hypertension in malaria endemic areas or at least in hypertensive patients with malaria.