Posted on 10/14/2019 10:45:03 AM PDT by BenLurkin
In the 1950s, researchers stumbled upon a new class of drugs that provided relief for those suffering from schizophrenia. These drugs were known as antipsychotics and, as the name suggests, they reduced symptoms like hallucinations and delusions — primarily by reducing the levels of dopamine in the brain. This led clinicians and scientists to argue that dopamine was linked to the experiences of psychotic symptoms, and a concerted research effort ensued, seeking to solve the puzzle of why excess dopamine might produce hallucinations.
Although it was later shown that increasing dopamine could produce hallucinations, establishing a consistent link between them, it has not been clear why.
They achieved this by taking advantage of a simple fact: Your brain is lazy. It makes shortcuts to understand the deluge of information that bombards it daily. If you’re presented with consistent information, consistently, your brain adjust its expectations of reality in turn. This is the basis of Bayesian theories of how we perceive the world – that is, the brain makes inferences about the world around us based on statistics and probabilities on what is likely to occur.
[I]ncreasing dopamine made it more difficult for participants to adjust their perception — an effect comparable to how the hallucinators had struggled. Moreover, the extent to which participants struggled was strongly associated with the severity of hallucinations — but not with any diagnosis of schizophrenia. In other words, the difficulty appeared to be associated with a symptom, not a diagnosis.
Using brain imaging, the researchers also showed that an increased capacity for dopamine release, from a part of the brain known as the striatum (an area involved in schizophrenia), was associated with the severity of hallucinations. Together, these experiments showed that excess dopamine was associated with difficulty in accurately predicting reality.
(Excerpt) Read more at inverse.com ...
I FELT LIKE I WAS HALLUCINATING THIS MORNING WATCHING FAT-A$$ NADLER’S IMPEACHMENT BULL$HIT
No ... THAT was real.
However, you may need significant adjustment for having wanted to put yourself through that.
To quote my Mother, “She just ‘ookie-dooked’ them!”
Tomorrow starts, (at the International Date Line), in the South Pacific.
Somehow that seems appropriate.
Wellnow. Jerry and Sharon came over and Jerry got all but two of the bolts in within 15 minutes and the last two took ten minutes. I told him to back the bolts out (”screws,” actually, but the thing was from a Canadian company so they dubbed them “bolts”) and I shined a light in the holes.
Gloriosky. The holes weren’t lined up properly. I searched through my meager supply of hardware and found some screws that are roughly the same length but just a little smaller in diameter, and they fit perfectly. They were tight because of the misalignment of the holes, and all I need is to paint them with black nail polish and no one will know.
Except all y’all. So tomorrow morning, I’ll turn to on the assembly of the frames to the mechanisms. Maybe by this time tomorrow, I’ll have a place for company to sit!
And then there’s the theme for The Blob playing in my head.
Thanks.
Super exciting. I like to sit!
There are many ladies similarly dressed in the Walmart here in Boring. It does show every cell.
Fortunately for me, when I shop, the aisles are clear of Walmartians and only the stalkers are in evidence. Dress code probably says something like, “No Spray-On Clothing.”
Kitteh is not biting his brother's tail. That's just your imagination.
Morning Floofy Squee is mischievous!
Good morning.
I slept in. Again. If I keep it up, it may become the norm. I’ll have to go to Walmart soon, but first, I had to sort my pills. It’s getting to the point that I loathe the job because it’s just 30+ minutes of standing in one spot. It’s not quite so bad since the epidural, but its still bad.
</whine
I’m excited about the futon/sofa, now, and need to get busy on the thank you gift. Walmart!
Can’t you sort your pills sitting down?
Good morning. Happy Trash Day! I need to haul some byos out of bed to get the trash out ;-).
I probably could sort the pills sitting but I’m so clumsy at odd moments that I would most likely knock over the pill sorter case when I was almost finished. Standing to do it is safer.
Back from Wally’s. I had to use de-icer on the windshield again, and the heater blew full force all the way to Walmart, and there was still moisture on the inside.
The nail polish was exactly the ticket! I even touched up the other bolts, because some of the anodized color had come off in the struggle to get them all seated.
I need to go put the dried clothes in the closet and then I should get busy on the thank-you gifts.
The byos are taking the trash out. I’ll have a shower between now and 8:45, when we’ll leave for WW.
The thought struck me when I was putting the polish on the bolt heads that back in the day, there were three colors of polish - red, pink and orange, and there was no such thing as black. There were shades of the colors but they were all distinct, but now there must be hundreds of shades.
My Trash Boy has been gone a long time. Funny how I was thinking about that the other day. Must be that time of year...
:o|
OTOH, kitteh could be biting kitteh’s own tail (kittehs being skilled practitioners of yoga).
That’s true. I have purple and blue. Sally uses black. The latest style in fingernails is very pointed, like hawks’ talons. It looks even worse than the previous fashion for squared-off ends.
I file mine with curved ends, as it should be.
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