Interesting. My dad was diagnosed with MS in his late 40s with no prior indications. After it progressed rapidly at first it stablized and has seen no major advance for 20 years.
They still have not figured out what initiates it. Though there has been conjecture on pockets of MS - genetic and geographic, they haven’t been able to pinpoint anything definitively. (unless I’ve missed research I’m unaware of).
My dads history and this research to me indicates that there is something causing the attack on the myelin to switch on and then when the initiator is dormant or gone it turns off the attack.
I had a friend who ran marathons. She had gotten MS when she was a young mother with 4 little ones under the age of 5. Husband was working in Fairbanks and they could never go outside, etc. She was absolutely sure/ and working on a PhD to put her theory into print/ that she had ‘given up’ with all the stress and her body had responded with MS.
She had gone to those faith healer/ Catholic/ witch doctors in the Phillipines - on a stretcher - and been healed.
(She died in an auto accident/ research not published).