I love wine, but only with food. Usually 1-2 times a week. Plus, I'm in high dollar, technical sales. Wine is often a "job requirement".
When I just want something to drink, I usually have bourbon on the rocks, or Canadian whiskey and Diet Coke. It's the fewest calories.
Interesting angle you have with gut bugs. I've often believed they play a more important role than most people think. I travel all over the world... I have mixed up gut bugs.
A good mix in the gut biome is ok. Also when traveling it is ok to get a little sick feeling the first few days adjust to even the water of whatever. Take good soil based probiotics THAT YOU ALSO TAKE AT HOME when you travel. Soil based not dairy based.
I dont drink but when I feel I have to socially I am going to order Gibsons or martinis (hate those green olives though) really dry.