What will be a huge problem is if they ever make an AI that is self-replicating.........................
Yep, I don’t imagine AI machines will have much use for ‘ugly bags of water’...
Very early SF treatment of that subject is the short story Mechanical Mice, by Maurice A. Hugi.
It is on the internet, if you know where to look.
Just Google the following words: "with mechanical aplomb", with quotation marks. They are the last three words of the story.
Originally published in Astounding Stories, back in 1941.