It lacks sufficient thickness to resist wind loading.
Stuff on the top floors will move when the wind blows.
The I value is inadequate
That was the first thing that came to my mind too. Doesn’t this duplicate the structure of the infamous Tacoma Narrows bridge, dubbed “Galloping Gertie” for its tendency to flex and pitch in high winds?
Admittedly, the winds on Manhattan Island probably don’t match those of the Tacoma Narrows, but I would think the stresses might be comparable. And Galloping Gertie ended up IN Puget Sound, rather than passing OVER it.