As fantasy is included...
The Lord of the Rings - Tolkien
The Space Trilogy - CS Lewis ( only Christian SF ever written )
If fantasy is included, one series that left me spellbound, enwrapt in delicious literary bondage, was The Chronicles of Thomas Covenant the Unbeliever by Stephen R. Donaldson.
10 books to tell the tale; it is not for the commitment-phobic ;)
I am not sure where One Hundred Years Of Solitude would fit in.
I read that and absolutely hated it. the books got progressively creepier, and the last book, That Hideous Strength, just pushed me over the edge. It gave me the willies.
Never again.
Excellent read...
My Freeper handle is from the CS Lewis space trilogy. That Hideous Strength is one of the most prescient books I have ever read. That said, there is a bunch of great Christian sci-fi besides that.
Gene Wolfe, RA Lafferty, the tragic Walter M. Miller all wrote and in Gene Wolfe’s case still write.
Freegards
The “Infinite Space, Infinite God” sci-fi anthology series is also Christian science fiction.
Look up Castalia House (Vox Day).
John C. Wright is very good.
For non-Christian stuff, Keith Laumer's Retief short stories and novels, and of course, Poul Andersons Polyseotechnic civilization saga (Nicholas van Rijn), and the Dominic Flanders novels.