Soooo... AppLocker. AppLocker has been around for a while now. This is just old technology wrapped in a new name. It’s contingent upon companies to actually turn on the protections to make them work. Nothing is “native” in corporate Windows.
There are a number of outfits doing similar things. Bit9, Carbon Black, TripWire,...
But it's nice to see the technology that was around only in the high-end editions of Windows make it into the more common ones (if I'm interpreting this right).