Guns are legal, drugs are not so apples and oranges comparisons are something conservatives should rue? Conservatives have had enough of liberal antics.
Guns, freedom of speech, religion, but drugs and abortion, and gay marriage, are a more difficult argument.
Some guns are not legal under federal law, via the Commerce Clause. A few state legislatures are beginning to tell the feds to butt out of their internal gun policies. Missouri comes to mind.
So do you support the expansive Commerce Clause over the 10th Amendment in those cases?