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To: FredZarguna

I propose there may be SNPs ‘like’ the ccr5 d32 mutation that confers partial immunity to HIV infection.


48 posted on 10/11/2014 5:01:11 PM PDT by Black Agnes
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IN THE NEAR FUTURE:

>Woman saves three relatives from Ebola

pays for plane tickets to U.S.


49 posted on 10/11/2014 5:08:54 PM PDT by RBStealth (--raised by wolves, disciplined and educated by nuns.)
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To: Black Agnes
I propose there may be SNPs ‘like’ the ccr5 d32 mutation that confers partial immunity to HIV infection.

True, and that possibility is what I allude to in post #39. However, in order to develop a resistant sub-population a cytologic immunity would require earlier epidemics that killed large numbers of non-resistant people [or, alternatively, the fecundity of those with better resistance would have to be significantly higher than the background population ... which seems very far fetched.]

Unless that happened, we have no reason to believe that a sub-population of Africans with resistance was any more likely than a sub-population of Asians or Europeans with resistance. And that is my point: we have no evidence of an outbreak that would lead to a higher than normal expression of a resistant genome in any modern or colonial history. The preference of expression for alleles requires environmental pressure. And we just don't have any evidence of that.

51 posted on 10/11/2014 5:19:56 PM PDT by FredZarguna (His first name is 'Unarmed,' and his given middle name is 'Teenager.')
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