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Primary immune-mediated thrombocytopenia in cats
National Center for Biotechnology Information ^ | Jan-Feb 2010 | National Center for Biotechnology Information

Posted on 12/03/2013 4:32:00 PM PST by Sioux-san

Just got home from the vet's office - took my 3 year old male cat in because he was not eating, drinking or doing anything but short walks around the room for the past two days. This was a highly energetic cat, goes outsideto play but stays inside during the night. Just had his vaccinations a few months ago. No reaction as far as I could tell until this. Now the vet tells me he has a very rare condition known as Primary immune-mediated thrombocytopenia: his immune system is attacking his platelets. The vet says it could be a reaction to the vaccine he had, and I wasn't charged for the visit. They are going to contact the drug company and see if this will be taken care of.

Has anyone out there in Freeper Land dealt with this? I don't know how much to put him through. It's incurable, but symptoms can be treated - I just retired...don't have thousands to put into this... geeeeez...he looks so miserable.


TOPICS: Pets/Animals
KEYWORDS: kittyping
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1 posted on 12/03/2013 4:32:00 PM PST by Sioux-san
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To: Sioux-san

Poor little guy. Prayers for him.


2 posted on 12/03/2013 4:37:30 PM PST by fieldmarshaldj (Resist We Much)
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To: Sioux-san
If it's anything like human ITP the ‘cure’ of choice is to remove the spleen. In humans it can be caused by a virus. Has your cat been sick? Is there a surgical option?
3 posted on 12/03/2013 4:38:54 PM PST by Vor Lady (Tagline still waiting to access Obamacare website......)
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To: Sioux-san
No advice, just prayers.

/johnny

4 posted on 12/03/2013 4:40:07 PM PST by JRandomFreeper (Gone Galt)
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To: Slings and Arrows

ping


5 posted on 12/03/2013 4:41:09 PM PST by Focault's Pendulum (I live in NJ....' Nuff said!)
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To: Sioux-san

My daughter had it a few years ago. Almost killed her. Spent 18 days in intensive care. She’s fine now. She had HUS/TCP=
Hemolytic Uremic Syndrome/Thrombocytopenia.

I can’t advise you on your cat. I can only sympathize.


6 posted on 12/03/2013 4:41:40 PM PST by Lucas McCain
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To: Sioux-san

The Power of the Dog

There is sorrow enough in the natural way
From men and women to fill our day;
And when we are certain of sorrow in store,
Why do we always arrange for more?
Brothers and Sisters, I bid you beware
Of giving your heart to a dog to tear.

Buy a pup and your money will buy
Love unflinching that cannot lie—
Perfect passion and worship fed
By a kick in the ribs or a pat on the head.
Nevertheless it is hardly fair
To risk your heart for a dog to tear.

When the fourteen years which Nature permits
Are closing in asthma, or tumour, or fits,
And the vet’s unspoken prescription runs
To lethal chambers or loaded guns,
Then you will find—it’s your own affair—
But...you’ve given your heart for a dog to tear.

When the body that lived at your single will,
With its whimper of welcome, is stilled (how still!);
When the spirit that answered your every mood
Is gone—wherever it goes—for good,
You will discover how much you care,
And will give your heart for the dog to tear.

We’ve sorrow enough in the natural way,
When it comes to burying Christian clay.
Our loves are not given, but only lent,
At compound interest of cent per cent.
Though it is not always the case, I believe,
That the longer we’ve kept ‘em, the more do we grieve:
For, when debts are payable, right or wrong,
A short-time loan is as bad as a long—
So why in Heaven (before we are there)
Should we give our hearts to a dog to tear?

Rudyard Kipling

Substitute cat, and the sentiment is the same when the final prescription runs
to lethal chambers or loaded guns.

/johnny


7 posted on 12/03/2013 4:42:27 PM PST by JRandomFreeper (Gone Galt)
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To: Sioux-san

I’m a marrow donor for a child with this disease.


8 posted on 12/03/2013 4:44:18 PM PST by AppyPappy (Obama: What did I not know and when did I not know it?)
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To: Sioux-san

My wife has Idiopathic Thrombocytopenia. Had no idea cats got it! She was bruising at the drop of a hat. After multiple attempts with different meds she finally had her spleen removed in 2001. She’s not had a problem with it since. The primary medication when first diagnosed was prednisone. It boosted her platelet count quickly and was very inexpensive. It does have some bad side effects such as bone loss-swelling-insomnia. Is some type of steroid treatment available for cats??


9 posted on 12/03/2013 4:49:27 PM PST by SpartacusII
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To: Sioux-san

Poor little guy. I hope your vet can successfully treat this so your pal can get back to being his cute zippy little self.


10 posted on 12/03/2013 4:59:06 PM PST by EinNYC
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To: Sioux-san
I can't help you with this specific disease, but I note the treatment includes transfusions and prednisolone. I had a cat that malabsorption syndrome that ultimately turned into lymphoma. His primary treatment for several years was prednisolone, which is an anti inflammatory. The only message I have is that he had a death sentence diagnosis, but lived a reasonable quality life for about three additional years with a very cheap drug. Also, if your cat is anemic with this condition, a common injectable drug called epogen may be used to increase red blood cell production. None of this may be helpful to your situation, but it is a couple of ideas.
11 posted on 12/03/2013 5:01:43 PM PST by Truth29
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To: AppyPappy

That is awesome. I hear donating bone marrow is kind of painful. My sister has a claim on my kidney if they can get all the paperwork and tests done.


12 posted on 12/03/2013 5:03:28 PM PST by GeronL (Extra Large Cheesy Over-Stuffed Hobbit)
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To: Sioux-san
We noticed this spring that one of our female cats wasn't eating, drinking and was lethargic and losing weight. The vet suspected that her immune system was attacking her liver. This is a really nice animal.

The vet did a blood count test and that is what it revealed. He hydrated her then gave us some antibiotics and a steroid to administer. The antibiotic was to prevent any possibility of infection.

The steroid was to overcome the desire of the immune system to destroy her liver.

After several trips to the vet, she is now normal, like her active self. We are still giving her a mild dose of steroid. We go in the 13th to have her rechecked.

13 posted on 12/03/2013 5:13:22 PM PST by Parmy
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To: Sioux-san

Sorry to hear this news about your little buddy. Hopefully, the drug company will provide some form of help if this is a reaction. I would also contact MSU veterinary teaching hospital: http://cvm.msu.edu/hospital/information-for-clients.


14 posted on 12/03/2013 5:15:05 PM PST by fivecatsandadog (If Obama is a brilliant writer (or brilliant anything), then I'm Bo Derek.)
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To: GeronL

Nah, not that painful. It won’t even get in the same room as Gout.


15 posted on 12/03/2013 5:21:08 PM PST by AppyPappy (Obama: What did I not know and when did I not know it?)
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To: AppyPappy

Really? I didn’t know that. Maybe you re just tougher than average.


16 posted on 12/03/2013 5:23:49 PM PST by GeronL (Extra Large Cheesy Over-Stuffed Hobbit)
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To: Sioux-san
The vet says it could be a reaction to the vaccine he had,

My cat is about 11 years old, stays indoors, and the only vaccines she's had are the ones she got prior to me adopting her........

Let me modify that, back in 2006 she did receive a feline leukemia vaccination but that is it. As expected, she was out of sorts for a day or two..........

With that being said, I don't recommend letting your cat outside and if you do that then there is no need in subjecting it to unneeded vaccines which makes them ill...........

Letting a cat outdoors is a personal choice but one has to weigh all the cons of letting them out as to the advantages of just keeping them in the house.....

I hope your kitty gets well.....

17 posted on 12/03/2013 5:27:44 PM PST by Hot Tabasco (Miss Muffit suffered from arachnophobia.....)
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To: GeronL

It’s not a matter of tough. Pain doesn’t bother me. I’ve never taken anything stronger than an Advil


18 posted on 12/03/2013 5:30:02 PM PST by AppyPappy (Obama: What did I not know and when did I not know it?)
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To: Sioux-san

Lots of big words and they all sound very scary. And they may be. You precious kitty has a low platelet count and in extreme cases there is an additional attack against white cells and other blood producing marrow. Fundamentally, this is an auto immune disease. I don’t know what additional your vet is doing but there are some protocols out there to help. Prognosis is unknown because each animal is so individual and what the overall health of the animal was before onset, etc etc.

Love your kitty. Check what kind of food you are feeding to be sure you have American made ( not some off shore unknown). Push your vet to see what additional can be done. Say lots of prayers.

Big heart felt hugs from here. I hope you and your cat have a long life together


19 posted on 12/03/2013 5:36:31 PM PST by Nifster
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To: Sioux-san

Several years ago, one of my cats developed thrombocytopenia and hemolytic anemia, both immune system mediated, most likely the result of a drug reaction.

We found her in the closet, severely underweight and yellow. We took her to the UC Davis teaching hospital. She was there for about 3 weeks, and was treated with steroids and an anti-leukemia chemotherapy drug. The first steroid was prednisolone for about a week, then she was switched to something else, but I do not remember what it was. She received heparin to treat blood clotting. Because of the platelet problem, she had blood clots all over her body, including in her lungs and heart. They kept her in an oxygenated incubator (the same kind used for premature babies), but had a DNR sign on it because of the clots. She received a blood transfusion and would have received another except that the donor cat developed an infection where the blood was drawn for the transfusion. The donor cat was her daughter.

When we finally brought her home, I had to give her pills and injections several times a day. I think it took about 3 or 4 months for her to recover fully.

All of this treatment was about $3,000, back in 1998. However, I consider it money well-spent, because she lived for another 9 years and died at the ripe old age of 18 of kidney failure. I also never had her vaccinated after that, because I was afraid that a vaccine might put her immune system into overdrive and she would not survive a second episode of the autoimmune disease. Not having her vaccinated did hamper our lifestyle somewhat, since not being able to board her meant we could never take vacations as a family. We also had to take her in the car with us during moves because airlines will not take unvaccinated animals (we prefer to drive ourselves but have the cats flown when we move).

Bottom line is that a cat can pull through this, but the treatment is labor-intensive and quite expensive. I hope my experience helps you decide what to do.


20 posted on 12/03/2013 5:37:32 PM PST by exDemMom (Current visual of the hole the US continues to dig itself into: http://www.usdebtclock.org/)
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