>>Everybody has the genes to metabolize alcohol except some people dont.
Not sure I see what you’re getting at. To metabolize is to process through the body. To extract energy and new materials, and to remove undesired materials. Everyone’s body metabolizes alcohol. I’m an alcoholic, and I make a conscious choice every day to be sober, because it’s the right thing to do.
That creates a serious social problem ~
I suppose there are other causes of alcoholism ~ perhaps various sorts of liver damage.
The only part of it under the control of the victim is to make sure alcohol consumption is within the ability of the body to metabolize it in a relatively short time.