1. Sucrose is composed of fructose and glucose in a 50/50 ratio.
2. HFCS is composed of fructose and glucose in about the same ratio as sucrose (either 55/45 or 42/58).
3. The fructose and glucose in HFCS and sucrose are chemically identical.
4. The fructose and glucose in HFCS and sucrose are absorbed by the body from the gut in exactly the same way.
5. Glucose is metabolized by the same metabolic pathway in the body regardless of whether it comes from corn syrup, cane sugar, clover, sugar beet, honey, or a glucose IV drip.
6. The same is true for fructose.
7. There is very little de novo lipogenesis in humans.
8. The increase in fat deposits in the context of a hypercaloric diet is due to substrate oxidation being switched away from fats, for which there is relatively unlimited storage, to glucose, for which there is relatively limited storage. Most of the fat on one's hips was most recently fat that crossed one's lips.
Sorry, I should have said “glucose” instead of “sucrose”. Nonetheless, hfcs is conducive to ill health; better watch this:
http://www.youtube.com/watch?v=dBnniua6-oM