Some extra study on your part, too much to detail here, would show you that this statement is a belief, not a truism.
How can the operational science work fine if the entire premise that it's based on is wrong?
What "entire premise" do you refer to? If I read this right, you're saying that Creation science study somehow refutes the scientific method, or somehow refutes the observations and repetition that we're doing today? How so?
Young Earth Creation science says the world is only 6000 years old.
The physical evidence present and the observed physics of the radiometric decay of long half-life radioisotopes says that’s not possible.