By itself it maybe meaningless but on the contrary it's only in the big picture that it's meaningful. When you consider the whole context, ie every individual piece of evidence from Obama not remembering which hospital he was born in, to spending million+ dollars to concealing his certificate, to the hospital suddenly declaring it had 'destroyed' all hard copies, to the lack of witnesses to his birth, to his gramma claiming to have witnessed his birth in Kenya... ad inf.. suddenly this new find takes meaning.
One huge issue that needs to be pushed is the Charity Fraud issue. If Obama was not born at the hospital both Obama and the Hospital have a problem for using that letter to raise funds. Obama can claim he didnt know they were going to do that but he put the lie to paper.