I think that's generally true for nature around us, but those constants break down--for instance, we know that Newton's laws of motion don't apply to sub-atomic particles. Everything else does, but subatomic particles don't. Why? Don't know. But they don't. So you can't rely on Newton's laws to explain those things. Same is also true for space. We know enough to know that Space doesn't follow our rules.
That's the point: when we find the rules don't apply, we try to ascertain what the newly discovered rules are. Things like quantum physics are tools to help discern what the true underlying rules are. Just as Einsteinian rules supplanted Newtonian, new rules are being discovered that poke holes in some aspects of Einstein's.
Space may not follow our rules but it follows some rules.