I use 150mg per day and it reduces my
neuropathy (numbness) in both feet
I hope that it continues to improve your situation. I continue to take 1 capsule daily, instead of the three I took for several months. My neuropathy has not improved, but I do have occasional episodes of generalized tingling and discomfort that I believe I misinterpreted as actual sensation.
The blood level test done by my neurologist when I was taking 3 a day did show an abnormally high thiamine level, versus a very slightly low level before, so I continue with the daily dose. I have lost 30 pounds, and I walk 3+ miles (on a treadmill, 4+ mph, incline 10) almost every day. I used to be a runner, but neuropathy interferes with my balance so I use the treadmill and hang on to the bar.
But now I am 69, borderline diabetic, hypertensive, hypercholemic, arthritic, and suffering from both GERD and diverticulosis.