No, he specifically addresses "Does non-random suggest that the very instructions for all possible morphological changes are front loaded or pre-programmed into living things". See the "all possible" in there? That is why he later denies "rigidness" and "pre-determined".
Finally in the post-chat q&A session after the period containing the citation above, you will find this exchange.
cougar
OK, molecular networks have computational properties. Complex systems seem to have inherent natural order. How does this connect to the ongoing evolution of the system?
James Shapiro
Cougar, your question goes to the heart of the issue. The ability of cells to rewrite their hereditary information and their ability to regulate that process are fundamental to what I think of as a 21st Century view of evolution. We know a lot about the molecular mechanisms involved. Our understandinbg of the computational processes involved are the weak point.
You mean the Q&A session where this appeared?
“James Shapiro
Phil, I think the key problem is to get genuinely new inventions in evolution. This clearly happens. Otherwise we are back with the homunculus and preformationism.”