I think Moe feels that guilt knowing that she had been very sick. Remember that he said (they said) he put her in the ice bath. His regret is likely that he listened to Howard rather than call 9-11. That would have at least upset his plans for the rest of the week.
If I were Virgie, I would have fought like hell, just like she did, for both my daughter and my tiny, new grandchild.
Someone tld me once: "We expect to see our parents die someday but we never expect the death of our child and certainly never expect to lose a grandchild".
Virgie's heart has a big void. Please don't forget about her. She aches every day and wishes she had done more sooner. She's powerless because she's not wealthy. Daniel and Anna belong HERE in the USA. I know it will come someday and it will give Virgie some peace.
Here's something to remember wrt to the baby being in FLA. Moe said he had to move something for his brother....Could that something have been a "someone"?
Sounds like Anna's immune system was compromised on top of everything else. Haven't we all had those moments where we look back, and think that we should have done something else in a particular situation? Howard better watch out. People don't call him Big Moe for nothing.