[Southack]

"You are still stuck on permutations and combinations. The original statement was that every possible point mutation occurred. That means one change per variation. Demanding that every permutation of a long string be tested is absurd. That does not model the actual process."

How did your bacteria experiment obtain 20 million unique DNA sequences from 3*1953 variations?

[js1138]

Try reading what I say. I never ruled out the accumulation of changes. I merely said that evolution works on small changes at a time.

There is nothing wrong with your math. You have the correct number of possible permutations.

The problem is with your model of what is happening. The hand is not reshuffled for each generation.