[js1138]

Check out the actual article. The entire genome is not relevant to the experiment. The entire search space in the relevant gene was explored.

[Southack]

"Check out the actual article. The entire genome is not relevant to the experiment. The entire search space in the relevant gene was explored."

I read your article. It's a fantastic, promising experiment worthy of scientific praise.

But...

It doesn't support your wild-eyed claim that "There have been very recent experiments in heat resistant bacteria in which every possible point mutation in the relevant genes was observed."

20 million does not equal 4 to the 1953rd power.