So tell us the difference between a micro-mutation and a macro-mutation. I'm sure generations of biologists are awaiting your wisdom.

That was answered in post #159 and repeated (something apparently quite necessary for the current crowd on this thread) in post #191.
The answer won't change. Repeatedly re-asking the above question will obtain the same answers already given in the above-mentioned posts (if you care to save time and typing, something of which I'm not altogether convinced).