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>How does the whole NIATONIN thing work?
Telegram and FR | September 9, 2021 | Dr. Dmitry Kats (interpreted)

Posted on 09/09/2021 6:58:17 AM PDT by numberonepal

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This does not make sense to me. How is it that I can take niacin, it goes into my stomach, and then the first place I feel a tingle is my ears? Sometimes within 5 minutes? How does it get there? There is not even much blood in the ears, it’s mostly cartilage. And in 5 minutes? Just trying to imagine by what mechanism this is even possible.

I just completed 3 weeks. As circumstances would have it, I was able to reach 1200 N on Saturday. But that’s because on both Friday and Saturday, I actually had the free time after meals to do 2 doses - so the 1200 was split between them.

I decided to play around with ratios, since there seemed to be no rhyme nor reason to the ones I’d been trying lately and what their results were:

Friday after brunch, 250M/300N; and after supper 100M/400N.

Saturday after brunch, 200M/700N; and after supper 200M/500N.

Both times Friday and after brunch Saturday I had light tingling on the ears, face and neck. After supper Saturday, there was nothing. Yay! (I was surprised!)

Sunday I was back to my usual once a day, and took 200M and 700N, and had slight tingling again.


261 posted on 10/11/2021 9:02:50 AM PDT by 17strings (There are 2 means of refuge from the miseries of life, music & cats. - A. Schweitzer)
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To: numberonepal

OK, the 500mg with 1/4 cup of pistachios made a flush just about like the first time. Not fun but not terrible. My powdered melatonin came yesterday but the scale won’t be here until tomorrow. No matter what, I really want to stay around 250-300mg of Niacin once a day. I’ll take some convincing to do otherwise, at least for a while.


262 posted on 10/11/2021 11:21:28 AM PDT by Tennessee Conservative (My goal in life is to be the person my dog's think I am)
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To: Tennessee Conservative

You’ll be amazed when you go beyond 1000 mg.

For me, a little food, a quarter cup of pistachios, and then the niacin in 12 oz of warm water, sipped slowly, seems to work. I know everyone’s different, however.


263 posted on 10/11/2021 12:10:55 PM PDT by AZLiberty (Awaiting the return of the king -- and I don't mean Elvis.)
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To: AZLiberty

Most meds and supplements effect me twice as much as they do other people so I normally take the minimum of everything. Niacin has always made me nervous for some reason. I’m not sure why. I have an appointment for bloodwork in February and if the lower dose doesn’t show up as a problem somewhere I might increase it.

This time was a little different. The first time I only took about 150mg and had an intense flush. On Sunday I took 250mg and 1/4 cup of pistachios and didn’t have any flush. This time I took 500mg with 1/4 cup of pistachios and had a similar flush as the first time but it lingered in a strange way. When it started to go away there was itching and chills. My skin stayed sensitive for longer.

I might do 250mg with half as many pistachios next time and see how that does.


264 posted on 10/11/2021 12:48:45 PM PDT by Tennessee Conservative (My goal in life is to be the person my dog's think I am)
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To: Tennessee Conservative

Soak a cup of pistachios for 12-24 hrs. Drain, then blend with 2 cups milk. If you have kitchen scales weigh out 200g of that smoothie. That should be around 66 stachios. Do maffs for other amounts. You have to get to 1500-2000N twice or thrice a day for therapeutic effects to really kick in.


265 posted on 10/11/2021 1:29:16 PM PDT by numberonepal (WWG1WGA)
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To: numberonepal

🤣 probably wasting my time then. No way this body can take that much.


266 posted on 10/11/2021 1:37:24 PM PDT by Tennessee Conservative (My goal in life is to be the person my dog's think I am)
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To: AZLiberty; Tennessee Conservative

That slow sipping is something to consider. I find I have less chance of flush if I do that. I’m talking like 5 mins rather than gulping down all that niacin at once.

You should really try the pistachio “smoothie”. It’s a lot easier to get them in that way. The soaking will make for a smoother drink and wash away unwanted salt. I forgot to add in my previous post to add some honey (like 2T) to the blender. I chose one cup pistachios and 2 cups milk because it’s easy to do the math as this ends up being right around 600g.

Another thing is that eating the pistachios will bring down your mellie requirements fairly quickly. I was downing a half cup of pistachios for 2000N, but now it’s more like 1/3. I’m not flushing so I may be able to go lower.


267 posted on 10/11/2021 1:40:19 PM PDT by numberonepal (WWG1WGA)
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To: Tennessee Conservative

It sounds counterintuitive, but the higher doses of niacin will result in less flush if you ratio the same mellie.


268 posted on 10/11/2021 1:41:15 PM PDT by numberonepal (WWG1WGA)
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To: Tennessee Conservative

It can if you get enough mellie in. You’re in the squirt gun range and you want to be in the firehose range.


269 posted on 10/11/2021 1:42:07 PM PDT by numberonepal (WWG1WGA)
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To: numberonepal

When I was still doing the pure melatonin, I began to think that a ratio didn’t describe the relationship. It’s more like the body needs a certain dose of melatonin to get things started (maybe absorbed by the intestinal bacteria) and then the ratio applies after that.


270 posted on 10/11/2021 1:50:09 PM PDT by AZLiberty (Awaiting the return of the king -- and I don't mean Elvis.)
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To: numberonepal

I put some pistachios in my fruit smoothie the other day. It was... interesting. Okay, however I wasn’t used to any salty taste in fruit smoothies.

But I hate milk.... gakkk! Haven’t consumed any since elementary school!


271 posted on 10/11/2021 1:54:24 PM PDT by 17strings (There are 2 means of refuge from the miseries of life, music & cats. - A. Schweitzer)
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To: numberonepal; Tennessee Conservative
You’re in the squirt gun range and you want to be in the firehose range.

I'm in the garden hose range, according to the meme. When I get to the fire hose range, I fear I'm going to be levitating off the acupuncture recliner, like Snuffles:


272 posted on 10/11/2021 1:55:56 PM PDT by AZLiberty (Awaiting the return of the king -- and I don't mean Elvis.)
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To: AZLiberty
Do you love to laugh, too?


273 posted on 10/11/2021 2:25:19 PM PDT by 17strings (There are 2 means of refuge from the miseries of life, music & cats. - A. Schweitzer)
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To: AZLiberty

274 posted on 10/11/2021 7:58:07 PM PDT by numberonepal (WWG1WGA)
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To: 17strings

I do it in my smoothie too but it kills most of the sweet.


275 posted on 10/11/2021 7:58:59 PM PDT by numberonepal (WWG1WGA)
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To: AZLiberty

Kats had some people try 15mg mellie and 1000mg niacin at the same time in one glass. No pistachios involved here. They are saying they didn’t flush but it seems to be veterans trying it. It sounds promising for a daily dose after going to therapeutic levels and back.


276 posted on 10/11/2021 8:01:12 PM PDT by numberonepal (WWG1WGA)
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To: numberonepal

I did 1412N tonight (because I didn’t want to scoop off 12 mg from the pile of niacin). Just had a few pistachios beforehand. Seems like there’s a form of pistachio persistence.

I’m taking about 1.5 oz (by weight) of pistachios per day. I’ll start cutting back on P when I reach 2000N to see what I really need.

Are people seeing benefits from going beyond 2000N?


277 posted on 10/11/2021 10:20:34 PM PDT by AZLiberty (Awaiting the return of the king -- and I don't mean Elvis.)
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To: numberonepal

I’ve read where people frequently speculate that you just get used to the niacin over time and don’t flush any longer, so the melatonin doesn’t make that much difference to the flushing issue, if any. This evidently happened with people who were on the niacin protocol before it became the niatonin protocol.

I tried another experiment tonight. 200M and 800N. But this time, knowing I’d likely get tingles, I prepared for it. I took a dollop of aloe vera gel, and mixed in a smidgen of melatonin powder until it dissolved. I massaged this into my skin in all the usual places that got tingles. Ears, face, neck, shoulders. And it really helped! And I know I was tingling because this time, I only felt it *inside* of my ears (that was a first!), the one spot I didn’t put the gel! Also, my eyes dried out, like they usually do when I tingle. So that’s another way to get melatonin to work. Interdasting!


278 posted on 10/11/2021 10:31:26 PM PDT by 17strings (There are 2 means of refuge from the miseries of life, music & cats. - A. Schweitzer)
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To: 17strings

That’s cool about the melatonin skin treatment.

I just wondered whether pistachio butter was a thing. It turns out that both Walmart and Safeway have it, though (at least in Walmart’s case) it’s mixed with walnut oil and salt.


279 posted on 10/12/2021 12:12:22 AM PDT by AZLiberty (Awaiting the return of the king -- and I don't mean Elvis.)
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To: 17strings

Interesting. I’ve made a melatonin, niacin and hyaluronic acid castor oil lotion for other purposes. If I flush on a dose I’ll try it out.


280 posted on 10/12/2021 7:20:44 AM PDT by numberonepal (WWG1WGA)
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